Analysis and clinical application of morphologic abnormalities warnings of the system XE2100 hematology analyzer

Objective To find the rule of the optical examine with microscope after the samples were analysed by the automated hematology analyzer (Sysmex XE2100),so as to provide a reliable evidence for clinical diagnosis and treatment.Methods A total of 4 758 samples were analyzed by the analyzer.We decided the samples for optical examination based on the warning-information,scatter diagrams and IG% parameters provided by the analyzer and patients′ historical data.Results In the 4 758 samples, there were 15.5%(722/4 758) samples had an abnormal information expression on the analyzer.We analyzed these samples by microscope and made a listing analysis for these test results in the meanwhile.With the analyzer Flag warning increasing from 100 to 300,the microscopic positive rate were gradually increased.With the IG% parameters increasing from 0.5 to 3.0, the microscopic positive rate were gradually increased.When the IG% parameters was 3.0,the microscopic positive rate could be 95.5%.Conclusions It is difficult that the analyzer can get a complete and correct analysis result if an abnormal sample is confronted with. We should make a optical examination with microscope according to the Flag-warning information, scatter diagram and IG% parameters,so that some valuable test information should be provided for the clinical work.