Clinical Meaning on Variation of Coagulation Indexes in Normal Pregnant Inducedhypertension

Objective:To evaluate the clinical signification of coagulation indexes prothrombin time(PT),activated partial thromboplastintime(APTT),plasma thrombin time(TT),fibrinogen(Fib) in normal pregnancywomen induced hypertension.Methods:PT、APTT、TT、Fib were assayed using oagulation method,all the peremeters were finished by ACL7000 automated blood coagulation analyzer.Reagent come from Dade Behring Marburg GmBh.Results: PT、APTT、TT,were significantly shorter and Fbg was higher in middle and later terms pregnancy women than that in normal women controls or early terms pregnancy women(P0.05或P0.01).Conclusion:The normal pregancy women and patients with pregnancy induced hypertension have many changes in coagulation system,showing a pregnancyrelated hypercoagulate.state existing risks of thrombotic complication.Observation of PT、APTT、TT and Fbg is necessary.