Clinical Meaning on Variation of Coagulation Indexes in Normal Pregnant Inducedhypertension

Objective To evaluate the clinical signification of coagulation indexes prothrombin time (PT),activated partial thromboplastintime (APTT),plasma thrombin time (TT),fibrinogen (Fib) in normal pregnancywomen induced hypertension.Methods PT、APTT、TT、Fib were assayed using oagulation method,all the peremeters were finished by CA-1500 automated blood coagulation analyzer.Reagent come from Dade Behring Marburg GmBh.Results PT、APTT、TT,were significantly shorter and Fbg was higher in middle and later terms pregnancy women than that in normal women controls or early terms pregnancy women (P0.05或P0.01).Conclusion The normal pregancy women and patients with pregnancy induced hypertension have a much changes in coagulation system,showing a pregnancy-related hypercoagulate.state existing risks of thrombotic complication.Observation of PT、APTT、TT and Fbg is necessary.