Clinical research on cross-matched test in patients with platelet transfusion refractoriness
Shaohua Zhang
Abstract
Shaohua Zhang
Abstract
Objective:To study the accidence of the platelet transfusion refractoriness(PTR),and analyze the clinical effect of cross-matched test in the PTR.Method:The platelet associated antibody of 265 patients were examined by SEPSA ways,who repeatedly transfused blood more times and transfused platelet more than three times,and the effect of platelet transfusion after cross-matched transfusion were observed.Result:There were 25 PTR in 265 patients(9.43%),19 of 25 PTR(76%)were found positive of platelet antibody,and in the 19 patients,12 ones(63.2%)were successfully cross-matched.Conclusion:Platelet antibody might lead to PTR.Cross-matched transfusion could enhance the effect of platelet transfusion and improve the clinical efficacy.
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Objective:To study the accidence of the platelet transfusion refractoriness(PTR),and analyze the clinical effect of cross-matched test in the PTR.Method:The platelet associated antibody of 265 patients were examined by SEPSA ways,who repeatedly transfused blood more times and transfused platelet more than three times,and the effect of platelet transfusion after cross-matched transfusion were observed.Result:There were 25 PTR in 265 patients(9.43%),19 of 25 PTR(76%)were found positive of platelet antibody,and in the 19 patients,12 ones(63.2%)were successfully cross-matched.Conclusion:Platelet antibody might lead to PTR.Cross-matched transfusion could enhance the effect of platelet transfusion and improve the clinical efficacy.
Key concepts: Platelet, Medicine, Platelet transfusion, Antibody, Refractory period, Blood transfusion, Internal medicine, Refractory (planetary science)