2012Journal of Clinical HematologyRequires access

Clinical research on cross-matched test in patients with platelet transfusion refractoriness

Shaohua Zhang

Open publisher page 0 citations

Abstract

Objective:To study the accidence of the platelet transfusion refractoriness(PTR),and analyze the clinical effect of cross-matched test in the PTR.Method:The platelet associated antibody of 265 patients were examined by SEPSA ways,who repeatedly transfused blood more times and transfused platelet more than three times,and the effect of platelet transfusion after cross-matched transfusion were observed.Result:There were 25 PTR in 265 patients(9.43%),19 of 25 PTR(76%)were found positive of platelet antibody,and in the 19 patients,12 ones(63.2%)were successfully cross-matched.Conclusion:Platelet antibody might lead to PTR.Cross-matched transfusion could enhance the effect of platelet transfusion and improve the clinical efficacy.

About this research paper

What this paper is about

Objective:To study the accidence of the platelet transfusion refractoriness(PTR),and analyze the clinical effect of cross-matched test in the PTR.Method:The platelet associated antibody of 265 patients were examined by SEPSA ways,who repeatedly transfused blood more times and transfused platelet more than three times,and the effect of platelet transfusion after cross-matched transfusion were observed.Result:There were 25 PTR in 265 patients(9.43%),19 of 25 PTR(76%)were found positive of platelet antibody,and in the 19 patients,12 ones(63.2%)were successfully cross-matched.Conclusion:Platelet antibody might lead to PTR.Cross-matched transfusion could enhance the effect of platelet transfusion and improve the clinical efficacy.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective:To study the accidence of the platelet transfusion refractoriness(PTR),and analyze the clinical effect of cross-matched test in the PTR.Method:The platelet associated antibody of 265 patients were examined by SEPSA ways,who repeatedly transfused blood more times and transfused platelet more than three times,and the effect of platelet transfusion after cross-matched transfusion were observed.Result:There were 25 PTR in 265 patients(9.43%),19 of 25 PTR(76%)were found positive of platelet antibody,and in the 19 patients,12 ones(63.2%)were successfully cross-matched.Conclusion:Platelet antibody might lead to PTR.Cross-matched transfusion could enhance the effect of platelet transfusion and improve the clinical efficacy.

Key concepts: Platelet, Medicine, Platelet transfusion, Antibody, Refractory period, Blood transfusion, Internal medicine, Refractory (planetary science)

Related papers

Back to paper searchBrowse research topicsOriginal source
Clinical research on cross-matched test in patients with platelet transfusion refractoriness — Research Paper | ScholarLens