Comparison of anesthesia induction with fentanyl and remifentanil on agitation during anesthesia recovery period in laparoscopic cholecystectomy patients

Objective: To compare the anesthesia induction with fentanyl and remifentanil on agitation during anesthesia recovery period in laparoscopic cholecystectomy patients. Methods: ASAⅠ or Ⅱ laparoscopic cholecystectomy patients were randomly divided into remifentanil group( R group) and fentanyl group( F group),to observe restlessness score. Inducing drugs: R group remifentanil 1 μg / kg,midazolam 3 mg,propofol 2 mg / kg,rocuronium 0. 6 mg / kg; F group were fentanyl 3. 0 μg / kg replace remifentanil,others medication with agree R group accord. To maintain anaesthesia by micro pump constant velocity input remifentanil 0. 2 μg·kg- 1· min- 1propfol 2 mg · kg- 1·h- 1and inhaling 1%- 2% sevoflurane. Compare agitation score in two groups before extubation, extubation,10 min after extubation. Results: Restlessness score in R group were higher than those in F group before extubation, extubation,10 min after extubation( P 0. 01). Differences of two groups of patients with spontaneous breathing recover time,awake time were not significant( P 0. 05). Conclusions: Anesthesia induction with fentanyl can effectively reduce agitation during anesthesia recovery period in laparoscopic cholecystectomy patients.