Remifentanil combined with propofol for observation of hypertensive elderly laparoscopic cholecystectomy

Abastract:Objective To explore the influence of remifentanil on laparoscopic gallbladder surgery in older patients with hypertension. Methods In 40 cases under general anesthesia undergoing laparoscopic cholecystectomyin elderly patients with hypertension were randomly divided into remifentanil group(group A) and fentanyl group(group B), propofol 0.1~0.15 mg /(kg·min) for maintenance and operation in group A and 0.1~0.5 μg /(kg·min) with remifentanil intravenous micro pump maintain,postoperative 30 min plus 0.05 mg fentanyl,B group with fentanyl 0.05 mg intravenous intermittent bolus 1 ~2, propofol 0.15 ~0.3 mg /(kg·min) maintenance of anesthesia. The MAP, HR, extubation time and wake rating of patients were recorded. Results After pneumoperitoneum,the values of MAP and HR in operation and postoperative extubation of the remifentanil group(group A) were significantly lower than those of the fentanyl group(group B)(P 0.05). Group A has shorter extubation time and better recovery score than group B(P 0.05). Conclusion In laparoscopic surgery of old patients with hypertension, remifentanil can maintaincirculation stability, has faster recovery of spontaneous breathing, wakes quickly, and reduces the stress response.