Analysis of clinical and laboratory of 228 cases of early syphilis in Nanning

Objective To analyse clinical manifestation of early syphilis and the laboratory techniques of diagnosis. Methods 228 cases of early syphilis in STD clinic and gynecology clinic in Nanning from May,2000 to May,2002 were summarized. Results 56 of 228 cases were primary syphilis(24.6%),appearance rate of typical chancres at genital organ was 32.14%,atypical chancres 67.86%.130 of 228 were secondary syphilis(57.0%).The appearance rate of dark_red macules at palm and sole sites and condyloma flat as the clinical characteristic lesions were 52.31% and 21.54% respectively.Three laboratory techniques were evaluated in the diagnosis of those patients. Ag?TRUST as a screening method and TPPA as a confirmation test,which have been widely used at present, showed a low sensitivity (69.9%? 83.4%? 67.9% respectively) to primary syphilis.Conclusion Secondary syphilis is the major clinical type at present in Nanning. and dark_red macules at palm and sole sites and condyloma flat are important diagnosis clue to secondary syphilis.Primary syphilis may be easily lost and misdiagnosised from early diagnosis because of atypical chancres and high negtive reaction to the three laboratory techniques. [