Analysis of Effect and Mechanism of Infections after Gynecological Operation by Adjuvant Therapy with Xianfanghuoming Decoction

Objective:To investigate the Xianfanghuoming auxiliary treatment effect and the mechanism of infection,to provide reference for clinical prevention and control of postoperative infection.Methods:300 cases of gynecologic operation were randomly divided into observation group and control group with 150 cases in each group.The control group received conventional perioperative medication to prevent postoperative infection.The observation group added Xianfanghuoming Decoction.The postoperative infection rate,changes and immune serum were compared in two groups.Results:The incidence rate was 0.67% of infected patients in the observation group,higher than that of the control group 4.67%.Two groups had significant difference(P 0.05).The observation group's hospitalization time,feeding time,bed time,postoperative medication costs were lower than those of the control group.The difference was statistically significant(P 0.05).After the surgery,two group's CD+3,CD+4,CD+4/CD+8were significantly improved(P 0.05); 3d,5d after the operation,observation group's CD+3,CD+4,CD+4/CD+8were higher than that of the control group and CD+8was lower than that in the control group.The differences were statistically significant(P 0.05).3d,5d after surgery the PCT,CRP,WBC levels were lower than that before operation(P 0.05).The observation group decreased levels were superior to those of the control group.The differences were statistically significant(P 0.05).Conclusion:In patients with gynecological operation,Xianfanghuoming Decoction can effectively reduce the postoperative infection rate,improve the indexes of serum and immune function of patients,shorten the time of recovery of patients.It is worthy of clinical application.