Clinical significance of second pathological examination in the diagnosis and treatment of cervical intraepithelial neoplasia

Objective To clarify the clinical significance of the second pathological examination of colposcopic biopsy and 1oop electrosurgical excision procedure(LEEP) in the diagnosis and treatment of cervical intraepithelial neoplasia(CIN).Methods 105 cases of CINⅠ~Ⅲ diagnosed by colposcopic biopsy were treated by LEEP.The pathological results of colposcopy biopsy and LEEP were analyzed.Results The pathology of LEEP and colposcopy biopsy in 70 cases was consistent,accounting for 66.67%(70/105).The pathology in 35 cases were not in consistence(33.33%,35/105),including 18 cases of upgradation(17.14%,18/105),and 17 cases of downgradation(16.19%,17/105).Conclusion There are still some difference of pathological results between LEEP and colposcopic biopsy in the diagnosis and treatment of CIN.The final diagnosis should be based on the higher level detected.LEEP has the dual role of diagnosis and treatment for CIN,thus serving as a more ideal treatment for CIN.