2009Journal of Medical ForumRequires access

Low-dose Cyclosporine A Combined Androgenin Treatment of Aplastic Anemia

Zhang Yusheng

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Abstract

Objective To explore clinical efficacy of the low-dose cyclosporine A combined androgen treatment of aplastic anemia.Methods Total 46 cases of aplastic anemia patients were randomly divided into observation group and control group,control group with androgen treatment,the observation group based on the control group treated with CsA 3 mg /(kg·d),Oral.Treatment for at least 3 months,stop it if void,if effective continue to take 3 to 6 months reduction,discontinuation of treatment and follow-up observation.Results The two groups of patients have been treated and the overall efficiency of the observation group was 86.9%,65.2% for the control group,two groups has statistical significance(P0.05).Group before and after treatment to observe changes in hemogram comparison there was a significant difference(P0.05).Conclusion Cyclosporine A combined androgen in treatment of aplastic anemia are effective treatment programs,and its not only safe,reliable,and less adverse reactions,it is worth clinical application.

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Objective To explore clinical efficacy of the low-dose cyclosporine A combined androgen treatment of aplastic anemia.Methods Total 46 cases of aplastic anemia patients were randomly divided into observation group and control group,control group with androgen treatment,the observation group based on the control group treated with CsA 3 mg /(kg·d),Oral.Treatment for at least 3 months,stop it if void,if effective continue to take 3 to 6 months reduction,discontinuation of treatment and follow-up observation.Results The two groups of patients have been treated and the overall efficiency of the observation group was 86.9%,65.2% for the control group,two groups has statistical significance(P0.05).Group before and after treatment to observe changes in hemogram comparison there was a significant difference(P0.05).Conclusion Cyclosporine A combined androgen in treatment of aplastic anemia are effective treatment programs,and its not only safe,reliable,and less adverse reactions,it is worth clinical application.

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Available abstract

Objective To explore clinical efficacy of the low-dose cyclosporine A combined androgen treatment of aplastic anemia.Methods Total 46 cases of aplastic anemia patients were randomly divided into observation group and control group,control group with androgen treatment,the observation group based on the control group treated with CsA 3 mg /(kg·d),Oral.Treatment for at least 3 months,stop it if void,if effective continue to take 3 to 6 months reduction,discontinuation of treatment and follow-up observation.Results The two groups of patients have been treated and the overall efficiency of the observation group was 86.9%,65.2% for the control group,two groups has statistical significance(P0.05).Group before and after treatment to observe changes in hemogram comparison there was a significant difference(P0.05).Conclusion Cyclosporine A combined androgen in treatment of aplastic anemia are effective treatment programs,and its not only safe,reliable,and less adverse reactions,it is worth clinical application.

Key concepts: Medicine, Aplastic anemia, Discontinuation, Anemia, Treatment and control groups, Androgen, Adverse effect, Statistical significance

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