ScholarLens Back to search
2000•Zhonghua shenjing waike zazhiRequires access

Expression of proliferating cell nuclear antigen (PCNA) in progressive astrocytomas

Jianming Wu

Open publisher page 0 citations

Abstract

Objective To examine the relationship between immunohistochemical expression of the proliferating cell nuclear antigen(PCNA) and pathology grade in astrocytomas, to discuss the value of PCNA in astrocytoma prognosis estimation.Methods A SP immuohistochemical staining technique was under taken for detection the expression of PCNA in 101 astrocytomas, in which, 22 cases had specimen of varying pathology areas. Results The percents of PCNA positive labeling cells increased along with the growing of pathology grade in astrocytomas. Conclusion This study suggests that the determination of PCNA is an useful indicator for the astrocytomas prognosis estimation.

About this research paper

What this paper is about

Objective To examine the relationship between immunohistochemical expression of the proliferating cell nuclear antigen(PCNA) and pathology grade in astrocytomas, to discuss the value of PCNA in astrocytoma prognosis estimation.Methods A SP immuohistochemical staining technique was under taken for detection the expression of PCNA in 101 astrocytomas, in which, 22 cases had specimen of varying pathology areas. Results The percents of PCNA positive labeling cells increased along with the growing of pathology grade in astrocytomas. Conclusion This study suggests that the determination of PCNA is an useful indicator for the astrocytomas prognosis estimation.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective To examine the relationship between immunohistochemical expression of the proliferating cell nuclear antigen(PCNA) and pathology grade in astrocytomas, to discuss the value of PCNA in astrocytoma prognosis estimation.Methods A SP immuohistochemical staining technique was under taken for detection the expression of PCNA in 101 astrocytomas, in which, 22 cases had specimen of varying pathology areas. Results The percents of PCNA positive labeling cells increased along with the growing of pathology grade in astrocytomas. Conclusion This study suggests that the determination of PCNA is an useful indicator for the astrocytomas prognosis estimation.

Key concepts: Proliferating cell nuclear antigen, Immunohistochemistry, Astrocytoma, Pathology, Antigen, Staining, Biology, Surgical pathology

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Expression of proliferating cell nuclear antigen (PCNA) in progressive astrocytomas — Research Paper | ScholarLens