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2003•The Chinese Journal of DermatovenereologyRequires access

Effect fo BCG-PSN on Patients with Condyloma Acuminatum

Shi Zhen

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Abstract

Objective To study the effect of BCG-PSN on the patients with condyloma acuminatum(CA).Methods Double-antibody sandwich ELISA was used to study the serum levels of interleukin-10 (IL-10)and interferon-gamma (IFN-γ)in normal people and CA patient (before and after treatment with or without BCG-PSN).Results Before treatment,the serum levels of IL-10 were significantly higher,while the levels of IFN-γ were significantly lower than that in normal people.There was a significantly negative correlation between IL-10 and IFN-γ.After treatment, the levels of IL-10 in the BCG group were decreased while the levels of IFN-γ were increased.There was no significant changes in comparing group.Conclusion Treatment with BCG-PSN can adjust the unbalant cytokine production in CA patient.

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What this paper is about

Objective To study the effect of BCG-PSN on the patients with condyloma acuminatum(CA).Methods Double-antibody sandwich ELISA was used to study the serum levels of interleukin-10 (IL-10)and interferon-gamma (IFN-γ)in normal people and CA patient (before and after treatment with or without BCG-PSN).Results Before treatment,the serum levels of IL-10 were significantly higher,while the levels of IFN-γ were significantly lower than that in normal people.There was a significantly negative correlation between IL-10 and IFN-γ.After treatment, the levels of IL-10 in the BCG group were decreased while the levels of IFN-γ were increased.There was no significant changes in comparing group.Conclusion Treatment with BCG-PSN can adjust the unbalant cytokine production in CA patient.

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Available abstract

Objective To study the effect of BCG-PSN on the patients with condyloma acuminatum(CA).Methods Double-antibody sandwich ELISA was used to study the serum levels of interleukin-10 (IL-10)and interferon-gamma (IFN-γ)in normal people and CA patient (before and after treatment with or without BCG-PSN).Results Before treatment,the serum levels of IL-10 were significantly higher,while the levels of IFN-γ were significantly lower than that in normal people.There was a significantly negative correlation between IL-10 and IFN-γ.After treatment, the levels of IL-10 in the BCG group were decreased while the levels of IFN-γ were increased.There was no significant changes in comparing group.Conclusion Treatment with BCG-PSN can adjust the unbalant cytokine production in CA patient.

Key concepts: Condyloma Acuminatum, Medicine, Cytokine, Immunology, Interferon, Gastroenterology, Antibody, Internal medicine

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