Preliminary analysis of left ventricular systolic synchrony and its systolic function in patients with myocardial infarction using three-dimensional echocardiography

Objective:To assess the left ventricular systolic synchrony and systolic function,and the relation between left ventricular systolic synchrony and its systolic function in the patients with myocardial infarction using real-time three-dimensional echocardiography (RT-3DE).Method:Twenty healthy subjects and thirty patients with myocardial infarction were enrolled and underwent RT-3DE.Then full-volume imaging was performed and the data was analyzed offline with software.A series of global and regional left ventricular volume curves were plotted.The parameters of left ventricular systolic function and synchrony in global and regional cardiac ventricle were all got.Data were grouped separately for 3 levels of the basal,mid and apical segments.Result:The ESV and EDV were larger and the LVEF was lower in the group of patients with myocardial infarction than the control group (P0.01).All the systolic synchrony parameters were significant larger in the patients with myocardial infarction (P0.001).The LVEF values were negative correlation with all the systolic synchrony parameters.Significant correlations was present between Tmsv-16-SD and LVEF (r=-0.644,P0.01).Compared with control group,the Tmsv-sel-SD and Tmsv-sel-Dif were lager,and the REF was lower in the group of patients with anterior myocardial infarction.The values of Tmsv-sel-SD and Tmsv-sel-Dif were negatively correlated with REF in apical segment of anterior myocardial infarction (r=-0.656,-0.687,P0.05).Conclusion:The RT-3DE can objectively evaluate left ventricular systolic synchrony and systolic function.The left ventricular systolic asynchrony can bring negative effect to systolic function.There were intimately correlations between systolic synchrony and systolic function in apical segment of anterior myocardial infarction.