Three-dimensional echocardiographic assessment of left ventricular systolic synchrony and systolic function in patients with myocardial infarction

Objective To assess left ventricular systolic synchrony and systolic function,as well as the relationship between left ventricular systolic synchrony and systolic function in patients with myocardial infarction with real-time three-dimensional echocardiography(RT-3DE).Methods Thirty patients with myocardial infarction and 20 healthy subjects underwent RT-3DE.Full-volume imaging was performed and the data was analyzed.A series of global and regional left ventricular volume curves were plotted.The parameters of left ventricular systolic function,synchrony in global and regional cardiac ventricle were obtained.Results ESV,EDV were larger and the LVEF was lower in the group of patients with myocardial infarction than those of the control group(P 0.01).All the systolic synchrony parameters were significant larger in patients with myocardial infarction than in the control group(P 0.001).The LVEF values,especially Tmsv-16-SD% and Tmsv-16-Dif%,were negative correlated with all the systolic synchrony parameters(r =-0.755,-0.747).The regional left ventricular systolic function parameters(rEF and rgEF)were lower and the Tmsv% was longer(P 0.05)in the zones with infarction in patients with anterior myocardial infarction than those of the control group.The changes of Tmsv% were in coincidence with that in regional left ventricular systolic function.Conclusion RT-3DE can be used to evaluate left ventricular systolic synchrony and systolic function.The left ventricular systolic asynchrony has negatively effect on systolic function.