The Clinical Significance of Serum Cystatin C for the Early Diagnosis of Diabetic Nephropathy

Objective To investigate the clinical significance of serum cystatin C(CysC),urinary N-acetyl-β-D-glucosaminidase(NAG),urinary albumin(mALB) for early diagnosis of diabetic nephropath.Methods Selected 60 cases of hospital patients with diabetes,of which urine protein negative has 31 patients,to be observtion group 1,positive in 29 cases for the observation group 2;also select medical centers over the same period of the same age as the normal physical examination with 40 patients in control group to measure diabetes group and control group blood cystatin C(CysC),urinary N-acetyl-βD-glucosaminidase(NAG),urinary albumin(mALB),while urinary creatinine(Cr).The results were in CysC,NAG/Cr,mALB/Cr said.Results Group 1 Group 2 with the observation of CysC,NAG/Cr,mALB / Cr was significantly higher indicators,significant differences between test results,with statistical significance P0.05;observation group 2 CysC,NAG/Cr,mALB/Cr was significantly higher than observed a group of indicators,significant differences between the results of the two groups,with statistical significance P0.05.Conclusion CysC,NAG/Cr,mALB/Cr can more accurately reflect the degree of renal damage in diabetic patients with the clinical detection of targets,the three early diagnosis of joint detection is a sensitive indicator of diabetic nephropathy.