2008Journal of Practical Medical TechniquesRequires access

Application of simvastatin in patients with acute coronary syndrome in early stage

Bin Yang

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Abstract

Objective To observe the influence of simvastatin on blood lipid and C-reactive protein(CRP) in patients with acute coronary syndrome(ACS).Methods 68 patients were divided into treatment group with simvastatin and control group without simvastatin,The treatment group receive simvastatin 20 mg/d,The blood lipid and C-reactive protein(CRP) were measured before and after the treatment.30 healthy people were measured as healthy control group.Results Patients with ACS had higher levels of CRP than those of healthy control group.After simvastatin treatment,the levels of TC and CRP were significantly deceased.Conclusion Simvastatin can reduce the levels of CRP and blood lipid evidently,has the effect of anti-inflammation and making piaquestable.

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What this paper is about

Objective To observe the influence of simvastatin on blood lipid and C-reactive protein(CRP) in patients with acute coronary syndrome(ACS).Methods 68 patients were divided into treatment group with simvastatin and control group without simvastatin,The treatment group receive simvastatin 20 mg/d,The blood lipid and C-reactive protein(CRP) were measured before and after the treatment.30 healthy people were measured as healthy control group.Results Patients with ACS had higher levels of CRP than those of healthy control group.After simvastatin treatment,the levels of TC and CRP were significantly deceased.Conclusion Simvastatin can reduce the levels of CRP and blood lipid evidently,has the effect of anti-inflammation and making piaquestable.

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Available abstract

Objective To observe the influence of simvastatin on blood lipid and C-reactive protein(CRP) in patients with acute coronary syndrome(ACS).Methods 68 patients were divided into treatment group with simvastatin and control group without simvastatin,The treatment group receive simvastatin 20 mg/d,The blood lipid and C-reactive protein(CRP) were measured before and after the treatment.30 healthy people were measured as healthy control group.Results Patients with ACS had higher levels of CRP than those of healthy control group.After simvastatin treatment,the levels of TC and CRP were significantly deceased.Conclusion Simvastatin can reduce the levels of CRP and blood lipid evidently,has the effect of anti-inflammation and making piaquestable.

Key concepts: Simvastatin, Medicine, C-reactive protein, Acute coronary syndrome, Internal medicine, Inflammation, Lipid profile, Blood lipids

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