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2014•Unpublished venueRequires access

The Changes of T lymphocyte subsets before and after Chemotherapy on 30 Ovarian Cancer Patients

DU Hong-y

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Abstract

Objective:To explore the changes of T lymphocyte subsets(CD3+、CD4+、CD8+、CD4+/CD8+)before and after chemotherapy on malignant Ovarian Cancer patients after their operations.Methods :After their operations, by flow cytometry, to detect the changes of quantities and ratios of T lymphocyte subsets in Ovarian Cancer patients before and during two- three weeks after the chemotherapy. Results :Compared the level before the chemotherapy, during two- three weeks after the chemotherapy, the levels of CD3+ and CD4+ cells were significantly higher,the ratio of CD4+/CD8+ increased, CD8+ cells had no obvious changes in different stage. Conclusion:The chemotherapy on malignant Ovarian Cancer patients is helpful in the recovery of the patients' immune functions of the cells.

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What this paper is about

Objective:To explore the changes of T lymphocyte subsets(CD3+、CD4+、CD8+、CD4+/CD8+)before and after chemotherapy on malignant Ovarian Cancer patients after their operations.Methods :After their operations, by flow cytometry, to detect the changes of quantities and ratios of T lymphocyte subsets in Ovarian Cancer patients before and during two- three weeks after the chemotherapy. Results :Compared the level before the chemotherapy, during two- three weeks after the chemotherapy, the levels of CD3+ and CD4+ cells were significantly higher,the ratio of CD4+/CD8+ increased, CD8+ cells had no obvious changes in different stage. Conclusion:The chemotherapy on malignant Ovarian Cancer patients is helpful in the recovery of the patients' immune functions of the cells.

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Available abstract

Objective:To explore the changes of T lymphocyte subsets(CD3+、CD4+、CD8+、CD4+/CD8+)before and after chemotherapy on malignant Ovarian Cancer patients after their operations.Methods :After their operations, by flow cytometry, to detect the changes of quantities and ratios of T lymphocyte subsets in Ovarian Cancer patients before and during two- three weeks after the chemotherapy. Results :Compared the level before the chemotherapy, during two- three weeks after the chemotherapy, the levels of CD3+ and CD4+ cells were significantly higher,the ratio of CD4+/CD8+ increased, CD8+ cells had no obvious changes in different stage. Conclusion:The chemotherapy on malignant Ovarian Cancer patients is helpful in the recovery of the patients' immune functions of the cells.

Key concepts: Medicine, Ovarian cancer, CD8, Chemotherapy, CD3, Lymphocyte subsets, Immune system, Flow cytometry

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