2004•Shanxi Yike Daxue xuebaoRequires access

Infection status of HBsAg positive pregnant women's newborns in Taiyuan city

Xiǎohóng Shí

Abstract

Objective To find out the infection status of HBsAg positive pregnant women' newborns in Taiyuan city. Methods HBsAg was determined by ELISA. HBV DNA was determined by nested PCR and PBMC HBV DNA was determined by selected PCR. The newborns were regarded as intrauterine infectious if any of the 3 markers was positive. Results The total HBV intrauterine infection rate was 37.75% . HBV intrauterine infection rates were 3.31% for HBsAg , 19.21% for HBV DNA and 23.84% for PBMC HBV DNA in newborns,respectively. Conclusion The detection of PBMC HBV is an important sumplement to the detection of serum HBV DNA. HBV intrauterine infection rate of HBsAg positive pregnant women's newborns is 37.75% in Taiyuan city, and it is lower compared with other study results.

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Key concepts: HBsAg, Medicine, Hepatitis B virus, Peripheral blood mononuclear cell, Pregnancy, Virology, Immunology, Infection rate