2010Chinese Journal of Hospital PharmacyRequires access

Influence on the two enteral nutrition method on nutritional status and prognosis in acute cerebral infarct patients

Cheng Zhou

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Abstract

OBJECTIVE To explore the influence of the two enteral nutrition method on nutritional status and outcome in acute cerebral infarct patients(72 h).METHODS Totally,80 acute cerebral infarct patients complicated with dysphagia were divided into two groups including sequential enteral nutrition group(SEN)and integral-protein enteral nutrition group(40 patients in each group).In the first three days patients in SEN group were nasally fed with short-peptide enteral nutrition(84-126 kJ ·kg-1·d-1)which would be replaced with integral-protein enteral nutrition from the forth day.Patients in control group were provided with integral-protein enteral nutrition by nasal feeding.Nutrition support for both groups lasted more than10 days.In the first,seventh and fourteenth day,data of both groups concerned with mean upper arm muscle circumference of triceps,serum albumen,serum prealbum,heamoglobin,incidence of infectious complications,neuro-function score(NHISS),Barthel Index and incidence of the gastrointestinal adverse reaction were collected and analyzed.RESULTS Nutritional indexes(serum prealbum,heamoglobin)in the group of the sequential enteral nutrition were significantly higher than those in integral-protein enteral nutritian group(P0.05)in the fourteenth day.we also found a significant decrease of infectious complications and incidence of the gastrointestinal adverse reaction in studied group compared to that in control group(P0.05-P0.01).Similar changes also could be seen in NHISS scores of two groups.But Barthel Index in studied group was statisitically higher than that in control group(P0.05).CONCLUSION The sequential enteral nutrition can improve the nutritional status in acute cerebral infarct patients and may be helpful for the impaired neuro-function recovery and improve the short-term prognosis.

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OBJECTIVE To explore the influence of the two enteral nutrition method on nutritional status and outcome in acute cerebral infarct patients(72 h).METHODS Totally,80 acute cerebral infarct patients complicated with dysphagia were divided into two groups including sequential enteral nutrition group(SEN)and integral-protein enteral nutrition group(40 patients in each group).In the first three days patients in SEN group were nasally fed with short-peptide enteral nutrition(84-126 kJ ·kg-1·d-1)which would be replaced with integral-protein enteral nutrition from the forth day.Patients in control group were provided with integral-protein enteral nutrition by nasal feeding.Nutrition support for both groups lasted more than10 days.In the first,seventh and fourteenth day,data of both groups concerned with mean upper arm muscle circumference of triceps,serum albumen,serum prealbum,heamoglobin,incidence of infectious complications,neuro-function score(NHISS),Barthel Index and incidence of the gastrointestinal adverse reaction were collected and analyzed.RESULTS Nutritional indexes(serum prealbum,heamoglobin)in the group of the sequential enteral nutrition were significantly higher than those in integral-protein enteral nutritian group(P0.05)in the fourteenth day.we also found a significant decrease of infectious complications and incidence of the gastrointestinal adverse reaction in studied group compared to that in control group(P0.05-P0.01).Similar changes also could be seen in NHISS scores of two groups.But Barthel Index in studied group was statisitically higher than that in control group(P0.05).CONCLUSION The sequential enteral nutrition can improve the nutritional status in acute cerebral infarct patients and may be helpful for the impaired neuro-function recovery and improve the short-term prognosis.

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Available abstract

OBJECTIVE To explore the influence of the two enteral nutrition method on nutritional status and outcome in acute cerebral infarct patients(72 h).METHODS Totally,80 acute cerebral infarct patients complicated with dysphagia were divided into two groups including sequential enteral nutrition group(SEN)and integral-protein enteral nutrition group(40 patients in each group).In the first three days patients in SEN group were nasally fed with short-peptide enteral nutrition(84-126 kJ ·kg-1·d-1)which would be replaced with integral-protein enteral nutrition from the forth day.Patients in control group were provided with integral-protein enteral nutrition by nasal feeding.Nutrition support for both groups lasted more than10 days.In the first,seventh and fourteenth day,data of both groups concerned with mean upper arm muscle circumference of triceps,serum albumen,serum prealbum,heamoglobin,incidence of infectious complications,neuro-function score(NHISS),Barthel Index and incidence of the gastrointestinal adverse reaction were collected and analyzed.RESULTS Nutritional indexes(serum prealbum,heamoglobin)in the group of the sequential enteral nutrition were significantly higher than those in integral-protein enteral nutritian group(P0.05)in the fourteenth day.we also found a significant decrease of infectious complications and incidence of the gastrointestinal adverse reaction in studied group compared to that in control group(P0.05-P0.01).Similar changes also could be seen in NHISS scores of two groups.But Barthel Index in studied group was statisitically higher than that in control group(P0.05).CONCLUSION The sequential enteral nutrition can improve the nutritional status in acute cerebral infarct patients and may be helpful for the impaired neuro-function recovery and improve the short-term prognosis.

Key concepts: Medicine, Parenteral nutrition, Incidence (geometry), Enteral administration, Barthel index, Gastroenterology, Internal medicine, Dysphagia

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