Clinical analysis of 46 cases with moderate or severe ovarian hyperstimulation syndrome

[Objective] To search for induced factors, clinical characteristics and therapy stralegy of moderate or severe ovarian hyperstimulation syndrome (OHSS). [Methods] Clinical data from 46 cases with moderate to severe OHSS were analyzed retrospectively. [Results] Most of OHSS occurred on the sixth day to sixteen day afer administration of medicine to enhanced ovulation.Abdominal distension,nausea, ascites, pleural effusion, edema, oliguria, concentrated blood, hypoalbuminemia, electrolyte and acid-base disturbance, and azotemia were the major manifestations of moderate or severe OHSS. Polycystic ovarian syndrome, young, thin and enhanced ovulation by HCG administration were high-risk factors for OHSS. All patients with OHSS got compietely recovery through intensive care, maintaining blood circulation, diuretics, abdominocentesis, and drainage. [Conclusions] We pay attention to prevent OHSS when enhancing ovulation. Intensive care is necessary in the treatment of moderate and severe OHSS.