Clinical Diagnostic Value of Serum Procalcitonin and C-Reactive Protein in Tumor Complicated with Infection

Objective: To investigate the clinical diagnostic value of serum procalcitonin( PCT) and C-reactive protein( CRP) in cancer patients complicated with infection. Methods: A total of 93 cases of cancer were divided into the group of tumor complicated with infection after chemoradiotherapy( group A,n = 33),the group of tumor complicated with infection without chemoradiotherapy( group B,n = 26),and the group of tumor with no infection( control group,n = 34). The venous blood was drawn for detection of serum PCT level by chemiluminescent immunoassay and detection of CRP level by immunoturbidimetry. The PCT level,CRP level and positive rates were compared between 3groups,and sensitivity and specificity in diagnosing tumor complicated with infection were analyzed.Results: The serum PCT and CRP levels in groups A and B were significantly increased compared with control group( P 0. 05). The positive rate of serum PCT was 84. 85% in group A and 88. 46% in group B,which were significantly higher than that in control group( P 0. 05). The positive rate of CRP was 96. 97% in group A and 96. 15% in group B,which were not significantly higher than that in control group( P 0. 05). The specificity of serum PCT and CRP in diagnosing tumor complicated with infection was 88. 24% and 14. 71%,respectively. Conclusion: Serum PCT is an effective indicator to diagnose tumor complicated with infection. The specificity of PCT is significantly better than that of CRP