Short-and long-term observation of ulcer with Helicobacter pylori negative treated by the method of TCM combined with western medicine

Objective To observe effect of short- and long-term of ulcer with Helicobacter pylori Negative treated by TCM combined with western medicine.Methods 84 patients with ulcer were randomly divided into control and treatment groups.In control group patients (n=40) were treated by Tagamet. In treatment group patients (n=44) were treated by combination of Yuyang decoction and Tagamet. Improvement of sign and symptoms in 1 week, 6 weeks and 1 year after treatment was evaluated.Results There was no significant difference on improving stomachache, acid regurgitation in 1 week after treatment between two groups (P0.05). Improvement of abdominal distention,bitter taste, fatigue and anorexia in treatment group was superior to those in control group (P0.05 or P0.01). The cure rate of peptic ulcer in treatment group was higher than that in control group (P0.05). Conclusion Combination of Yuyang decoction and Tagamet could effectively improve signs and symptoms caused ulcer with Helicobacter pylori.