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2007•Chinese Journal of Control of Endemic DiseasesRequires access

A study on the correlations between plasma concentrations of N-terminal pro brain natriuretic peptide and cardiac function in patients with chronic heart failure

YU Min-qi

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Abstract

Objective To study the correlations between plasma concentrations of N-terminal pro brain natriuretic peptide (NT-proBNP) with cardiac function in patients with chronic heart failure.Methods Plasma NT-proBNP levels of patients with cardiac diseases (n=120) and of normal controls (n=34) were measured by enzyme-linked immunoassay.Results The plasma NT-proBNP concentrations of patients with chronic heart failure were significantly higher than those of the normal controls and the cases with non heart failure respectively. They also increased with the severity of cardiac failure according to NYHA functional classification (P0.001).Conclusion The plasma NT-proBNP concentration is a important biochemical parameter for evaluating heart function.

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What this paper is about

Objective To study the correlations between plasma concentrations of N-terminal pro brain natriuretic peptide (NT-proBNP) with cardiac function in patients with chronic heart failure.Methods Plasma NT-proBNP levels of patients with cardiac diseases (n=120) and of normal controls (n=34) were measured by enzyme-linked immunoassay.Results The plasma NT-proBNP concentrations of patients with chronic heart failure were significantly higher than those of the normal controls and the cases with non heart failure respectively. They also increased with the severity of cardiac failure according to NYHA functional classification (P0.001).Conclusion The plasma NT-proBNP concentration is a important biochemical parameter for evaluating heart function.

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Available abstract

Objective To study the correlations between plasma concentrations of N-terminal pro brain natriuretic peptide (NT-proBNP) with cardiac function in patients with chronic heart failure.Methods Plasma NT-proBNP levels of patients with cardiac diseases (n=120) and of normal controls (n=34) were measured by enzyme-linked immunoassay.Results The plasma NT-proBNP concentrations of patients with chronic heart failure were significantly higher than those of the normal controls and the cases with non heart failure respectively. They also increased with the severity of cardiac failure according to NYHA functional classification (P0.001).Conclusion The plasma NT-proBNP concentration is a important biochemical parameter for evaluating heart function.

Key concepts: Heart failure, Internal medicine, N-terminal pro-Brain Natriuretic Peptide, Medicine, Cardiac function curve, Cardiology, Brain natriuretic peptide, Natriuretic peptide

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