Prognostic significance of left ventricular systolic function in acute coronary syndrome patients treated with PCI

Objective To determine clinical outcomes of acute coronary syndrome (ACS) patients with decreased left ventricular function after percutaneous coronary intervention (PCI). Methods 110 ACS patients were divided into two groups: normal left ventricular ejection fraction (NEF) group (n=61, male/female: 47/14) and decreased left ventricular ejection fraction (DEF) group (n=49, male/female: 42/7). Incidence of major adverse cardiovascular events (MACE, including cardiac death,recurrent non-fatal myocardial infarction, recurrent angina and chronic heart failure) was recorded. Results During 6 to 54 months follow-up,there was no significant difference between the two groups in incidence of MACE (P0.05), although there were more patients with large area anterior infarction and enlarged left ventricle in the DEF group (P0.05).Conclusion ACS patients with decreased left ventricular function could obtain similar clinical outcomes as patients with normal left ventricular function after PCI and aggressive medical therapy.