MRI and MRA diagnosis of moyamoya disease in adult(a report of 6 cases)

Objective:To analyze the MRI and MRA features of moyamoya diseases in adult.Method:MR appearances of 6 patients with moyamoya disease confirmed by DSA were analyzed retrospectively.MRI with SE,FSE sequences and 3D TOF MRA were performed on a GE 1.5T MR unit.Results:Moyamoya disease in adult appeared mostly as cortical cerebral is chemia and/or multiple lacunar infarction,encephalatrophy,and cerebral or subarachnoid hemorrhage.MRI showed no flow void in the occluded cerebral artery,and obvious flow void of extensive anastomotic network in thalamus and basal ganglia region.MRA demonstrated directly the stenosis or occlusion of the bifurcation of ICA,proximal portion of the ACA or MCA,and extensive anastomotic network.In comparison with DSA,MRA could accurately show the stenosis or occlusion of cerebral arteries and tortuous collateral circulation.Conclusion:MRI,together with MRA,is an effective noninvasive method for the diagnosis of moyamoya disease and suitable for screening to replace the procedure of DSA.