Comparison of insulin dose using glargine insulin and insulin pump

Objective:To explore the dose relationship between glargine insulin and insulin pump both used to provide patients with diabetes mellitus with basal insulin requirements. Methods:Patients with diabetes modulated their blood glucose concentration with insulin pump in an ideal level about 2 weeks,then removed insulin pump and used glargine insulin at bedtime and other hypoglycemia agents.The insulin doses were compared between glargine insulin and insulin pump therapy,their relationship were analyzed.Results:The insulin dose with glargine insulin is 35% of the total insulin dose and 50% of the basal insulin dose with insulin pump therapy.The coefficient variation is 0.77 and 0.74(P0.001).Conclusion:The first insulin dose with glargine insulin therapy may be 35% of the total insulin dose and 50% of the basal insulin dose with insulin pump treatment.