2004Jilin yixueRequires access

Evaluation of immunoturbidimetric method for measuring serum c-reactive protein

Xing Jin

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Abstract

Objective To evaluate the performance characteristics of the immunoturbidi-metric assay for Measurement of C-reac-tive Protein.Method The reproducibility and linearity of the method were determined.A method comparison study was performed using an single diffusion test as the reference test.Results The linearity range was found0.33~42mg /L.Reported values above42mg /L should be diluted and reanalyzed.The coefficients of variation were below5%.The comparison with the single diffusion test showed a good correlation coefficient (r=0.976,CRP values from2.77~28.65mg /L).Conclusion The method is easy to perform,ac-curate,fully automated,and suitable for analyzing a small number of samples.

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What this paper is about

Objective To evaluate the performance characteristics of the immunoturbidi-metric assay for Measurement of C-reac-tive Protein.Method The reproducibility and linearity of the method were determined.A method comparison study was performed using an single diffusion test as the reference test.Results The linearity range was found0.33~42mg /L.Reported values above42mg /L should be diluted and reanalyzed.The coefficients of variation were below5%.The comparison with the single diffusion test showed a good correlation coefficient (r=0.976,CRP values from2.77~28.65mg /L).Conclusion The method is easy to perform,ac-curate,fully automated,and suitable for analyzing a small number of samples.

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Available abstract

Objective To evaluate the performance characteristics of the immunoturbidi-metric assay for Measurement of C-reac-tive Protein.Method The reproducibility and linearity of the method were determined.A method comparison study was performed using an single diffusion test as the reference test.Results The linearity range was found0.33~42mg /L.Reported values above42mg /L should be diluted and reanalyzed.The coefficients of variation were below5%.The comparison with the single diffusion test showed a good correlation coefficient (r=0.976,CRP values from2.77~28.65mg /L).Conclusion The method is easy to perform,ac-curate,fully automated,and suitable for analyzing a small number of samples.

Key concepts: Medicine, Reproducibility, Linearity, Correlation coefficient, Coefficient of variation, Diffusion, Analytical Chemistry (journal), Chromatography

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