Study on the correlation between dyslipidemias and occurrence of acute cerebral infarction

Objective To investigate the relationship between dyslipidemia and occurrence of acute cerebral infarction.Methods 174 cases of acute cerebral infarction admitted to Traditional Chinese Medical Hospital of Zhejiang Province from October 2009 to October 2011 were selected as observation group and 110 cases of healthy people in the same period were chosen as control group.The serum levels of total cholesterol(TC),low-density lipoprotein cholesterol(LDL-C),high-density lipoprotein cholesterol(HDL-C) and triglyceride(TG) between the two groups were compared.Multiple Logistic regression analysis of acute cerebral infarction was applied to conduct the risk assessment.Results ①TC,LDL-C in observation group were(4.83±0.10) mmol/L and(2.83±0.09) mmol/L respectively,they all higher than those in control group [(4.42±0.14),(2.48±0.12) mmol/L],the differences were statistically significant(P 0.01);the level of HDL-C in observation group [(1.46±0.04) mmol/L] was lower than that in control group [(1.69±0.11) mmol/ L],the difference was statistically significant(P 0.05);the difference of TG in the two groups was not statistically significant [(1.71±0.10)mmol/L vs(1.50±0.13)mmol/L](P 0.05).②The detection rates of abnormal of TC,LDL-C and HDL-C in observation group [60.34%(105/174),72.99%(127/174),50.57%(88/174)] were higher than those in control group [60.34%(105/174),72.99%(127/174),50.57%(88/174)],the differences were statistically significant(P 0.01);the difference of detection rates of abnormal of TG was not statistically significant(P 0.05).③TC,LDL-C and HDL-C levels were important risk factors in acute cerebral infarction according to the Logistic regression analysis.Conclusion The abnormal levels of TC,LDL-C,HDL-C have intimate correlation with the occurrence of acute cere bral infarction.The decline of HDL-C is the sensitive index of acute cerebral infarction.