Relationship between Plasma Level of Brain Natriuretic Peptide and Clinical Manifestation and Prognosis of Patients with Acute Myocardial Infarction

Objective To observe the relationship between the plasma level of brain natriuretic peptide(BNP) and clinical manifestation of patients with acute myocardial infarction(AMI).Methods 72 patients with AMI were enrolled in this study.The plasma level of BNP was measured and the left ventricular ejection fraction(LVEF) was evaluated by echocardiography within 24 hours after admission.All patients were followed up for six months.Results The plasma level of BNP in the patients with AMI had a positive correlation with infarction areas,and negative correlation with LVEF(P0.05).The clinical cardiac events occurred more frequently in the patients with higher BNP level.Conclusion The plasma level of BNP in patients with AMI might be a reliable biochemical marker which can objectively evaluate the degree and prognosis of the disease.