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2006•Lishizhen Medicine and Materia Medica ResearchRequires access

Determination of the Content of Magnolol and Honokiol in Banxia-Houpu Effervescent Tablets by HPLC

Guo Wei

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Abstract

ObjectiveTo establish a method for determining the content of magnolol and honokiol in Banxia-Houpu effervescent tablets.MethodsMagnolol and honokiol were separated with Elite C_(18)column(4.6 mm × 200 mm,5μm) and detected at 294 nm,using methanol-acetonitrile-water(31.5∶38.5∶30.0)as mobile phase.ResultsThe standard curves for magnolol and honokiol were linear in the range of 0.54～13.61μg(r=0.999 7) and 0.11～2.82 μg(r=0.999 7).The average recoveries of magnolol and honokiol were 100.92%(RSD=1.79%) and 101.23%(RSD=1.79%).ConclusionThe method is simple and quick,which is suitable for practical use.

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What this paper is about

ObjectiveTo establish a method for determining the content of magnolol and honokiol in Banxia-Houpu effervescent tablets.MethodsMagnolol and honokiol were separated with Elite C_(18)column(4.6 mm × 200 mm,5μm) and detected at 294 nm,using methanol-acetonitrile-water(31.5∶38.5∶30.0)as mobile phase.ResultsThe standard curves for magnolol and honokiol were linear in the range of 0.54～13.61μg(r=0.999 7) and 0.11～2.82 μg(r=0.999 7).The average recoveries of magnolol and honokiol were 100.92%(RSD=1.79%) and 101.23%(RSD=1.79%).ConclusionThe method is simple and quick,which is suitable for practical use.

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Available abstract

ObjectiveTo establish a method for determining the content of magnolol and honokiol in Banxia-Houpu effervescent tablets.MethodsMagnolol and honokiol were separated with Elite C_(18)column(4.6 mm × 200 mm,5μm) and detected at 294 nm,using methanol-acetonitrile-water(31.5∶38.5∶30.0)as mobile phase.ResultsThe standard curves for magnolol and honokiol were linear in the range of 0.54～13.61μg(r=0.999 7) and 0.11～2.82 μg(r=0.999 7).The average recoveries of magnolol and honokiol were 100.92%(RSD=1.79%) and 101.23%(RSD=1.79%).ConclusionThe method is simple and quick,which is suitable for practical use.

Key concepts: Honokiol, Magnolol, Chromatography, High-performance liquid chromatography, Chemistry, Content determination

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Determination of the Content of Magnolol and Honokiol in Banxia-Houpu Effervescent Tablets by HPLC — Research Paper | ScholarLens