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Longitudinal Observation on The Effect of Praziquantel in Treatment of Fifty-Six Cases with Clonorchiasis

Lan Yang

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Abstract

Objective To study the effectiveness of repeated treatment with small dosag of prazipuantel (75mg/kg·d) in population in heavy epidemic are with clonorchis sinensis. Methods To carry out the survey in population with Kato-Katz. Results The infectious rate of intestinal parasites in population was 73. l%, of which the infectious rate of clenorchis sinensis was 37. 3%. Through four examinations and three treatments in two years, the egg negative conversion rate and egg eduction rate in 56 cases were 76. 8% and 9l. 6%, respectively. Conclusion This method with small dose for treatment of Patients with clonorchiasis in population is easy and safe for application in the mild and medium endemic area and the therapeutic result is satisfactory.

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Objective To study the effectiveness of repeated treatment with small dosag of prazipuantel (75mg/kg·d) in population in heavy epidemic are with clonorchis sinensis. Methods To carry out the survey in population with Kato-Katz. Results The infectious rate of intestinal parasites in population was 73. l%, of which the infectious rate of clenorchis sinensis was 37. 3%. Through four examinations and three treatments in two years, the egg negative conversion rate and egg eduction rate in 56 cases were 76. 8% and 9l. 6%, respectively. Conclusion This method with small dose for treatment of Patients with clonorchiasis in population is easy and safe for application in the mild and medium endemic area and the therapeutic result is satisfactory.

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Available abstract

Objective To study the effectiveness of repeated treatment with small dosag of prazipuantel (75mg/kg·d) in population in heavy epidemic are with clonorchis sinensis. Methods To carry out the survey in population with Kato-Katz. Results The infectious rate of intestinal parasites in population was 73. l%, of which the infectious rate of clenorchis sinensis was 37. 3%. Through four examinations and three treatments in two years, the egg negative conversion rate and egg eduction rate in 56 cases were 76. 8% and 9l. 6%, respectively. Conclusion This method with small dose for treatment of Patients with clonorchiasis in population is easy and safe for application in the mild and medium endemic area and the therapeutic result is satisfactory.

Key concepts: Clonorchiasis, Clonorchis sinensis, Praziquantel, Population, Infection rate, Medicine, Veterinary medicine, Internal medicine

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