Survey and Control Measures on Clonorchis sinensis in Kaiping City

Objective To study the epidemic status of Clonorchis sinensis infection in Kaiping city, and establish a diagnostic method for large scale of epidemiology investigation for Clonorchis sinensis. To set up effective control and prevention measures. Methods Clonorchis sinensis eggs in stool samples were detected by Kato Katy thick smear methods and Clonorchis sinensis specific antibodies of blood samples were detected by ELISA. Clonorchis sinensis infected individuals were also diagnosed with abdominal ultrasound scanning and treated with albendazole anti helminthes sweeties. And the investigation to intermediate and reservoir hosts had also been carried out. Results The total infection rate of Clonorchis sinensis in the local area was 34.1%. The infection rates of Dongfenghong village and Licun village were 34.8%and 33.3%, respectively. And the infection rates of male and female were 44.0%and 26.8%, respectively. The infection rate of 15～60 age group was higher than other age groups. The averge EPG of male and female were 200.2 and 164.8, respectively. The condition of 99.0%(374/377) infected individuals were mild. None showed hepatic and bile duct pathological changes. There was no significant difference in the infection rate determined by Kato Katy and ELISA methods. The negative conversion rate of 226 persons was 96.0%after albendazole anti helminthes sweeties therapy. Clonorchis sinensis larval was discovered in the fry of the local fish pools. Clonorchis sinensis imago was found in the local dogs and cats in the autopsy. Conclusions Clonorchis sinensis was endemic in the two villages of Kaiping city. ELISA diagnosis could replaced fecal examination in the large scale of epidemiology investigation for Clonorchis sinensis. Albendazole anti helminthes sweeties therapy could significantly controlled the infection of Clonorchis sinensis.