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Effect of medified electroconvulsive therapy on the cognition of patients with major depression disorder

Lou Dan-dan

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Abstract

Objective: To estimate the influence of modified electroconvulsive therapy(MECT) on the cognition of patients with major depression.Methods: Patients metting CCMD-3 criteria for major depression,whose scores of HAMD 17-item were above 24,were treated with bilateral,brief pulse,square-wave stimulus,dose titration MECT.Before and after the 1st and 6~8th course of treatment,Hamilton depression scale and Wechsler memory scale were tested.Results:There was significant amelioration of clinical symptoms after MECT(P 0.01),but it had negative impact on memory,which would last till the 6~8th course of treatment.Conclusion: MECT may improve the symptoms of patients with severe depression and irreversibly influnce the memory.

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What this paper is about

Objective: To estimate the influence of modified electroconvulsive therapy(MECT) on the cognition of patients with major depression.Methods: Patients metting CCMD-3 criteria for major depression,whose scores of HAMD 17-item were above 24,were treated with bilateral,brief pulse,square-wave stimulus,dose titration MECT.Before and after the 1st and 6~8th course of treatment,Hamilton depression scale and Wechsler memory scale were tested.Results:There was significant amelioration of clinical symptoms after MECT(P 0.01),but it had negative impact on memory,which would last till the 6~8th course of treatment.Conclusion: MECT may improve the symptoms of patients with severe depression and irreversibly influnce the memory.

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Available abstract

Objective: To estimate the influence of modified electroconvulsive therapy(MECT) on the cognition of patients with major depression.Methods: Patients metting CCMD-3 criteria for major depression,whose scores of HAMD 17-item were above 24,were treated with bilateral,brief pulse,square-wave stimulus,dose titration MECT.Before and after the 1st and 6~8th course of treatment,Hamilton depression scale and Wechsler memory scale were tested.Results:There was significant amelioration of clinical symptoms after MECT(P 0.01),but it had negative impact on memory,which would last till the 6~8th course of treatment.Conclusion: MECT may improve the symptoms of patients with severe depression and irreversibly influnce the memory.

Key concepts: Electroconvulsive therapy, Wechsler Adult Intelligence Scale, Hamd, Depression (economics), Cognition, Wechsler Memory Scale, Psychology, Hamilton depression scale

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Effect of medified electroconvulsive therapy on the cognition of patients with major depression disorder — Research Paper | ScholarLens