Analysis on Antimicrobial Resistance of Gram-negative Bacteria in Patient with Lower Respiratory Tract Infections

Objective To understand the antimicrobial resistance of gram-negative bacteria in patients with lower respiratory tract infections,and to provide the evidence for rational use of antibiotics in clinical practice.Methods The bacteria isolated from January,2007 to December,2008 in our hospital were indentified by conventional methods.A K-B test was used to analyze the antimicrobial susceptibility.Results Among 482 strains of gram-negative bacteria,there were 148 strains of Klebsiella,130 Escherichia coli,75 Acinetobacter baumannii,and 50 Pseudomonas aeruginosa,with the isolating rates of 30.71%,26.97%,15.56%,and 10.37%,respectively.Conclusions Klebsiella and Escherichia coli are the most important bacteria in patient with lower respiratory tract infections in our hospital,with the ESBLs isolating rates of 61.48% and 60.00%,respectively.