Effect of postoperative enteral nutrition on SOD,MDA and T lymphocyte subsets of elder patients with gastric cancer

Objective: To evaluate the effect of early enteral nutrition on SOD,MDA and T lymphocyte subsets in surgical elder patients with gastric cancer.Methods: 45 elder patients with gastric cancer were randomly divided into early enteral nutrition(EEN)group and control group(PN).The patients in EEN group received enteral nutrition from postoperative day1 to postoperative day 7.The patients in PN group received total parental nutrition.SOD,MDA and CD3+,CD4+,CD8+,CD4+/CD8+ were detected on the day before the operation and the postoperative day1 and 7.Results: As compared with the day before the operation,on postoperative day 1,the levels of SOD,CD3+,CD4+ and CD4+/CD8+ were decreased in two groups(P0.05).Then the change of MDA was not significant in EEN group and there was significant difference between two groups on postoperative day 7(P0.05).Negative correlation was found between the MDA and CD4+/CD8+(r=-0.774,P0.05).Conclusion: Early enteral nutrition can improve obviously cellular immunity function in gastric cancer surgical patients by regulating the changs of SOD and MDA.