2007•Xinjiang Yike Daxue xuebaoRequires access

Effect of early enteral nutrition on immune function in postoperative patients with gastric cancer

Haijiang Wang

Abstract

Objectives:To Investigate immune function effect of early enteral nutrition(EEN) in surgical patients with gastric cancer.Methods:Sixty patients with gastric cancer surgical patients were randomly divided into EEN group and parental nutrition(PN) group.The patients in EEN group received RUISU early enteral nutrition from postoperative day 1 to postoperative day 7.The patients in PN group received total parental nutrition.IgA,IgG,IgM,CD3+,CD4+,CD8+,CD4+/CD8+ were detected on the day before the operation and the postoperative days 1 and 8.Results:As compared with the day before the operation,postoperative day 1,all the levels of IgA,IgG,IgM,CD3+,CD4+ and CD4+/CD8+ in two groups were decreased.However,postoperative day 8,the changes in the EEN group was significantly different from PN group(P0.05).In both EEN group and PN group there were no serious complications.Conclusions:Compared with the parental nutrition,early enteral nutrition can improve obviously immune function in post operative patients with gastric cancer.

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Key concepts: Medicine, Parenteral nutrition, Immune system, Gastroenterology, CD8, Enteral administration, Internal medicine, Cancer