The Effects of Rosuvastatin on Hyperlipidemia Blood Lipids and High-Sensitivity C-reactive Protein of Elderly Patients with Coronary Heart Disease

Objective: To discuss the effects of rosuvastatin on hyperlipidemia blood lipids and high-sensitivity C- reactive protein of elderly patients with coronary heart disease. Methods: 68 patients with coronary heart disease and hyperlipidemia treated in my hospital from July 2012 to June 2013 were randomly divided into two groups, the control group(34 cases) was gave conventional treatment, on the basic of the control group, the observation group was gave rosuvastatin, with treattment period for 2 months. The level change of blood lipid and high-sensitivity C- reactive protein before and after treatment in the two groups were observed, and adverse reactions of two groups were Statistics during treatment. Results: The differences of TC, TG, LDL- C, HDL- C before treatment between the two groups was not significant, P0.05, and after treatment, TC, TG, LDL- C levels of two groups fallen, and HDL- C level raise, but TC, TG, LDL- C level after treatment in the observation group were significantly lower than that in the control group(P0.05), the level of HDL- C after treatment in the observation group were significantly higher than that in control group(P0.05). hs-CRP of treatment group before treatment was(3.86±1.12) mg/L, and hs-CRP of control group for(3.82 ±0.84) mg/L, there was no significant differences between the two groups(P 0.05), hs-CRP of treatment group after treatment was(2.57±0.66) mg/L, hs-CRP of control group for(3.23±0.66) mg/L, there was significant differences between the two groups(P 0.05). After treatment, patients in two groups appeared mild adverse symptoms, the incidence of adverse reactions in the treatment group was 8.82%, and the control group for 23.53%, with no significant differences between the two groups(x2= 0.497, P = 0.780 0.05). Conclusion: Rosuvastatin can effectively improve blood fat of coronary heart disease combined hyperlipidemia, and reduce high-sensitivity c-reactive protein, it is worth in the clinical treatment of coronary heart disease combined hyperlipidemia for more widely used.