2002Unpublished venueRequires access

OPERATION VERSUS INJECTION: A COMPARISON FOR THE TREATMENT OF KELOID

Wen Liu

Open publisher page 0 citations

Abstract

Objective To compare the effects of keloid treated with operation and injection. Methods 32 cases with keloid were divided into groups A and B. In Group A, triamcinolone solution was injected into keloid tissue and ointment was besmeared on keloid surface and covered with dressing. In Group B, triamcinolone solution was injected into keloid tissue 1-2 weeks before operation, and the lesion was then completely resected. A small amount of drug was injected into the incision 3 weeks after the operation to prevent scar formation. Results Group A (84 scars): cure, response and un response were 57, 26, and 1 respectively, the cure rate being 68%, and the total response rate 98%. Group B (32 scars): cure, response and un response were 12, 14 and 6 respectively, the cure rate being 37% and the total response rate 81%. The difference was significant between the two groups( u c=5.03, P 0.05). Conclusion The combination treatment (mainly by injection) has the advantage of high response rate but is poor in improving ones looks; operations may reduce the size of the lesion but with high recurrence rate. The treatment, therefore, should be carried in accordance with the individual condition.

About this research paper

What this paper is about

Objective To compare the effects of keloid treated with operation and injection. Methods 32 cases with keloid were divided into groups A and B. In Group A, triamcinolone solution was injected into keloid tissue and ointment was besmeared on keloid surface and covered with dressing. In Group B, triamcinolone solution was injected into keloid tissue 1-2 weeks before operation, and the lesion was then completely resected. A small amount of drug was injected into the incision 3 weeks after the operation to prevent scar formation. Results Group A (84 scars): cure, response and un response were 57, 26, and 1 respectively, the cure rate being 68%, and the total response rate 98%. Group B (32 scars): cure, response and un response were 12, 14 and 6 respectively, the cure rate being 37% and the total response rate 81%. The difference was significant between the two groups( u c=5.03, P 0.05). Conclusion The combination treatment (mainly by injection) has the advantage of high response rate but is poor in improving ones looks; operations may reduce the size of the lesion but with high recurrence rate. The treatment, therefore, should be carried in accordance with the individual condition.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective To compare the effects of keloid treated with operation and injection. Methods 32 cases with keloid were divided into groups A and B. In Group A, triamcinolone solution was injected into keloid tissue and ointment was besmeared on keloid surface and covered with dressing. In Group B, triamcinolone solution was injected into keloid tissue 1-2 weeks before operation, and the lesion was then completely resected. A small amount of drug was injected into the incision 3 weeks after the operation to prevent scar formation. Results Group A (84 scars): cure, response and un response were 57, 26, and 1 respectively, the cure rate being 68%, and the total response rate 98%. Group B (32 scars): cure, response and un response were 12, 14 and 6 respectively, the cure rate being 37% and the total response rate 81%. The difference was significant between the two groups( u c=5.03, P 0.05). Conclusion The combination treatment (mainly by injection) has the advantage of high response rate but is poor in improving ones looks; operations may reduce the size of the lesion but with high recurrence rate. The treatment, therefore, should be carried in accordance with the individual condition.

Key concepts: Keloid, Medicine, Triamcinolone acetonide, Cure rate, Lesion, Scars, Surgery, Complete response

Related papers

Back to paper searchBrowse research topicsOriginal source
OPERATION VERSUS INJECTION: A COMPARISON FOR THE TREATMENT OF KELOID — Research Paper | ScholarLens