STUDY ON THE RELATIONSHIP BETWEEN CAROTID ATHEROSCLEROSIS AND HIGH-SENSITIVITY C-REACTIVE PROTEIN AND IRON PROTEIN IN TYPE 2 DIABETIC PATIENTS

Objective To investigate the relationship and clinical significance between carotid atherosclerosis and serum levels of high sensitivity c reactive protein (Hs-CRP) and ferritin(SF) in patients with type 2 diabetes mellitus(T2DM). Methods According to the IMT and plaque,62 patients with T2DM were divided into two groups : IMT abnormal group: 38 and IMT normal group: 24, 40 healthy persons served as control . The levels of serum Hs-CRP and SF were measured respectively. All carotid arteries of 62 cases were examined with color Doppler ultrasound. Results The levels of IMT, serum Hs-CRP and SF in patients with T2DM were significantly higher than those in control group(p0 01); The levels of IMT, serum Hs-CRP and SF significantly increased in patients with T2DM and hypertension (p0 05) ;The levels of serum Hs-CRP and SF in IMT abnormal group were significantly higher than those in IMT normal group (p0 05). Conclusions The levels of serum Hs-CRP and SF may play an important role in progression of carotid atherosclerosis of T2DM. The increasing level of Hs-CRP and SF may signify the high risk of cardia-cerebrovascular complication in patients with type 2 diabetes mellitus.