Analysis on 249 Cases of Perioperative Application of Antibiotics in Cardiac Surgery Department of Our Hospital

OBJECTIVE:To evaluate the perioperative application of antibiotics in cardiac surgery department of our hospital.METHODS:By retrospective analysis,249 cases of perioperative application of antibiotics in cardiac surgery department of our hospital from Jan.2009 to Jun.2009 were analyzed statistically.RESULTS:Among 249 patients,244 patients received antibiotics before operation and 249 after operation.5 categories(7 kinds)of antibiotics were adopted before operations.Benzylpenicillin sodium occupied the highest proportion(146 cases),followed by cefotaxime sodium(101 cases).22 cases received two-drug therapy.;none of case used 3 kinds or more antibiotics.Only 30 cases have been received etiologic test and susceptibility test.The initial delivery time before operation was lower than 30 min.The shortest delivery time of antibiotics before operation was 1 d and the longest was 15 d with an average time of 5.87 d.The operations duration of 71 cases were more than 3 h and 178 cases lower than 3 h.None of case received additional antibiotics during the operations.CONCLUSION:There are some problems to deal with,such as inappropriate selection of drug category,unreasonable timing,delayed medication time and poor etiology test,etc.