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2006•Chinese Journal of Interventional CardiologyRequires access

Effect of tirofiban on TIMI flow in patients with STEMI during primary PCI

Ming Chen

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Abstract

Objective To eveluate the effect of tirofiban on TIMI flow in patients with STEMI during primary PCI. Methods Forty-eight patients with STEMI who underwent primary PCI were randomly divided into two groups which were: the tirofiban+PCI group (n=27) and the primary PCI group (n=21). The TIMI flow before and after the operation were reviewed angiographically. Results A greater percentage of TIMI 1 flow was archieved in the triofiban+PCI group compared with the primary PCI group before operation (37% vs 9.5%, P0.05). On the other hand, TIMI 0 flow was more commonly found in patients in the primary PCI group compared with the tirofiban+PCI group (38.1% vs 7.4%, P0.01). There was no difference in the archievement of TIMI 3 flow between the two groups after operation, but the occurance of TIMI 2 flow was less in the tirofiban+PCI group compared with the primary PCI group. Conclusion Tirofiban may improve TIMI flow of the IRA in patients with STEMI during primary PCI.

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Objective To eveluate the effect of tirofiban on TIMI flow in patients with STEMI during primary PCI. Methods Forty-eight patients with STEMI who underwent primary PCI were randomly divided into two groups which were: the tirofiban+PCI group (n=27) and the primary PCI group (n=21). The TIMI flow before and after the operation were reviewed angiographically. Results A greater percentage of TIMI 1 flow was archieved in the triofiban+PCI group compared with the primary PCI group before operation (37% vs 9.5%, P0.05). On the other hand, TIMI 0 flow was more commonly found in patients in the primary PCI group compared with the tirofiban+PCI group (38.1% vs 7.4%, P0.01). There was no difference in the archievement of TIMI 3 flow between the two groups after operation, but the occurance of TIMI 2 flow was less in the tirofiban+PCI group compared with the primary PCI group. Conclusion Tirofiban may improve TIMI flow of the IRA in patients with STEMI during primary PCI.

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Available abstract

Objective To eveluate the effect of tirofiban on TIMI flow in patients with STEMI during primary PCI. Methods Forty-eight patients with STEMI who underwent primary PCI were randomly divided into two groups which were: the tirofiban+PCI group (n=27) and the primary PCI group (n=21). The TIMI flow before and after the operation were reviewed angiographically. Results A greater percentage of TIMI 1 flow was archieved in the triofiban+PCI group compared with the primary PCI group before operation (37% vs 9.5%, P0.05). On the other hand, TIMI 0 flow was more commonly found in patients in the primary PCI group compared with the tirofiban+PCI group (38.1% vs 7.4%, P0.01). There was no difference in the archievement of TIMI 3 flow between the two groups after operation, but the occurance of TIMI 2 flow was less in the tirofiban+PCI group compared with the primary PCI group. Conclusion Tirofiban may improve TIMI flow of the IRA in patients with STEMI during primary PCI.

Key concepts: TIMI, Conventional PCI, Tirofiban, Medicine, Cardiology, Internal medicine, Myocardial infarction

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