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Analysis of the drug resistance of neisseria gonorrhoeae to 5 antibiotics

Yufeng Niu

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Abstract

Objective To survey the drug resistance of neisseria gonorrhoeae to 5 antibiotics and the prevalence of PPNG and TRNG in 2009.Methods Minimum inhibitory concentrations(MIC) of penicillin,ciprofloxacin,ceftriaxone and spectinomycin of neisseria gonorrhoeae were tested by using the agar dilution method,and β-lactamase was detected by paper iodin quantitative method.Results In 120 strains of neisseria gonorrhoeae,33 strains of PPNG accounted for 27.5%,and 52 strains of TRNG accounted for 43.3%.Drug resistant rates of ciprofloxacin and penicillin were 95.8%and 95.0%,respectively.The insolated strains were not resistant to ceftriaxone and spectinomycin.Conclusion It is important to analyze the antibiotic resistance of neisseria gonorrhoeae.

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Objective To survey the drug resistance of neisseria gonorrhoeae to 5 antibiotics and the prevalence of PPNG and TRNG in 2009.Methods Minimum inhibitory concentrations(MIC) of penicillin,ciprofloxacin,ceftriaxone and spectinomycin of neisseria gonorrhoeae were tested by using the agar dilution method,and β-lactamase was detected by paper iodin quantitative method.Results In 120 strains of neisseria gonorrhoeae,33 strains of PPNG accounted for 27.5%,and 52 strains of TRNG accounted for 43.3%.Drug resistant rates of ciprofloxacin and penicillin were 95.8%and 95.0%,respectively.The insolated strains were not resistant to ceftriaxone and spectinomycin.Conclusion It is important to analyze the antibiotic resistance of neisseria gonorrhoeae.

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Available abstract

Objective To survey the drug resistance of neisseria gonorrhoeae to 5 antibiotics and the prevalence of PPNG and TRNG in 2009.Methods Minimum inhibitory concentrations(MIC) of penicillin,ciprofloxacin,ceftriaxone and spectinomycin of neisseria gonorrhoeae were tested by using the agar dilution method,and β-lactamase was detected by paper iodin quantitative method.Results In 120 strains of neisseria gonorrhoeae,33 strains of PPNG accounted for 27.5%,and 52 strains of TRNG accounted for 43.3%.Drug resistant rates of ciprofloxacin and penicillin were 95.8%and 95.0%,respectively.The insolated strains were not resistant to ceftriaxone and spectinomycin.Conclusion It is important to analyze the antibiotic resistance of neisseria gonorrhoeae.

Key concepts: Neisseria gonorrhoeae, Spectinomycin, Penicillin, Ciprofloxacin, Microbiology, Ceftriaxone, Antibiotics, Agar dilution

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