ScholarLens Back to search
2004•Zhejiang Medical JournalRequires access

Relationship between cognitive function and regional cerebral blood flow in Alzheimer disease

Liu Qicang

Open publisher page 1 citations

Abstract

Objective To investigate the manifestations of rCBF(regional cerebral blood flow) in patients with Alzheimer's disease (AD) and the relationship between cognitive function and rCBF. Methods rCBF in 11 patients with AD and 10 non-demented elderly controls were analyzed. Results Compared with normal controls, there was significantly decreased rCBF in the bilateral temporal lobes, most part of parietal lobes and regional frontal lobes of the patients with AD. There was no significant difference of rCBF between right and left lobe in the AD patients. And there was a positive correlation between MMSE (Mini-Mental State Examination) scores and the rCBF of temporal lobe and left anterior parietal lobe. Conclusion The results suggest that rCBF might be useful in diagnosis and evaluation of the severity of AD.

About this research paper

What this paper is about

Objective To investigate the manifestations of rCBF(regional cerebral blood flow) in patients with Alzheimer's disease (AD) and the relationship between cognitive function and rCBF. Methods rCBF in 11 patients with AD and 10 non-demented elderly controls were analyzed. Results Compared with normal controls, there was significantly decreased rCBF in the bilateral temporal lobes, most part of parietal lobes and regional frontal lobes of the patients with AD. There was no significant difference of rCBF between right and left lobe in the AD patients. And there was a positive correlation between MMSE (Mini-Mental State Examination) scores and the rCBF of temporal lobe and left anterior parietal lobe. Conclusion The results suggest that rCBF might be useful in diagnosis and evaluation of the severity of AD.

Why it matters

OpenAlex reports 1 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective To investigate the manifestations of rCBF(regional cerebral blood flow) in patients with Alzheimer's disease (AD) and the relationship between cognitive function and rCBF. Methods rCBF in 11 patients with AD and 10 non-demented elderly controls were analyzed. Results Compared with normal controls, there was significantly decreased rCBF in the bilateral temporal lobes, most part of parietal lobes and regional frontal lobes of the patients with AD. There was no significant difference of rCBF between right and left lobe in the AD patients. And there was a positive correlation between MMSE (Mini-Mental State Examination) scores and the rCBF of temporal lobe and left anterior parietal lobe. Conclusion The results suggest that rCBF might be useful in diagnosis and evaluation of the severity of AD.

Key concepts: Cerebral blood flow, Medicine, Temporal lobe, Frontal lobe, Alzheimer's disease, Cardiology, Parietal lobe, Cognition

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Relationship between cognitive function and regional cerebral blood flow in Alzheimer disease — Research Paper | ScholarLens