Jiangmen city 3782 cases of peripheral blood chromosome analysis for genetic counseling

Objective: To study the relationship between abnormal of chromosome of people of geneic counseling and diseases by analyzing the chromosomal karyotype in patients of genetic counseling.Methods: To collect peripheral blood samples.Chromosome specimens were made using routine culture of peripheral blood lymphocytes.The G-band technique was used in the cytogenetical analysis.Results: 345 cases of chromosome abnormalities(9.12%) were detected in 3782 genetic consultants.There were 91 sex chtomosome abnormalities(27%) and 254 autosomal abnormalities(73%) Conclusion: Chromosome abnormality is a considerable reason for primary or secondary amenorrhea,spontaneous abortion and stillbirth history,mental and sexual development abnormity.Chromosomes detection is necessary for the genetic consultant.