ScholarLens Back to search
2007•Zhongguo yaofangRequires access

Study on Quality Standards for Yinlian Oral Solution

Weilin Chen

Open publisher page 0 citations

Abstract

OBJECTIVE: To establish the quality standards for Yinlian oral solution. METHODS: TLC was adopted to identify Radix Scutellariae, Rhizoma Coptidis, Fructus Forsythiae in Yinlian oral solution. HPLC was applied to determine the content of Baicalin in Yinlian oral solution, using Nova- Pak C18( 150mm× 4. 6mm, 4μ m) as column, the mixture of methanol- 0. 3% phosphoric acid ( 40∶ 60) as mobile phase, with flow rate set at 1. 0mL· min- 1 and detection wavelength at 276 nm. RESULTS: Radix Scutellariae, Rhizoma Coptidis and Fructus Forsythiae were clearly detected with TLC. The content of baicalin showed a good linear relationship at a range of 1. 68～ 16. 8μ g· mL- 1( r=0. 999 8) . The average recovery was 99. 06% ( RSD=0. 79% ) . CONCLUSIONS: The standard is accurate, reliable, and can be used for quality control of Yinlian oral solution.

About this research paper

What this paper is about

OBJECTIVE: To establish the quality standards for Yinlian oral solution. METHODS: TLC was adopted to identify Radix Scutellariae, Rhizoma Coptidis, Fructus Forsythiae in Yinlian oral solution. HPLC was applied to determine the content of Baicalin in Yinlian oral solution, using Nova- Pak C18( 150mm× 4. 6mm, 4μ m) as column, the mixture of methanol- 0. 3% phosphoric acid ( 40∶ 60) as mobile phase, with flow rate set at 1. 0mL· min- 1 and detection wavelength at 276 nm. RESULTS: Radix Scutellariae, Rhizoma Coptidis and Fructus Forsythiae were clearly detected with TLC. The content of baicalin showed a good linear relationship at a range of 1. 68～ 16. 8μ g· mL- 1( r=0. 999 8) . The average recovery was 99. 06% ( RSD=0. 79% ) . CONCLUSIONS: The standard is accurate, reliable, and can be used for quality control of Yinlian oral solution.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

OBJECTIVE: To establish the quality standards for Yinlian oral solution. METHODS: TLC was adopted to identify Radix Scutellariae, Rhizoma Coptidis, Fructus Forsythiae in Yinlian oral solution. HPLC was applied to determine the content of Baicalin in Yinlian oral solution, using Nova- Pak C18( 150mm× 4. 6mm, 4μ m) as column, the mixture of methanol- 0. 3% phosphoric acid ( 40∶ 60) as mobile phase, with flow rate set at 1. 0mL· min- 1 and detection wavelength at 276 nm. RESULTS: Radix Scutellariae, Rhizoma Coptidis and Fructus Forsythiae were clearly detected with TLC. The content of baicalin showed a good linear relationship at a range of 1. 68～ 16. 8μ g· mL- 1( r=0. 999 8) . The average recovery was 99. 06% ( RSD=0. 79% ) . CONCLUSIONS: The standard is accurate, reliable, and can be used for quality control of Yinlian oral solution.

Key concepts: Baicalin, Chromatography, Quality standard, Radix (gastropod), Phosphoric acid, Chemistry, High-performance liquid chromatography, Content determination

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Study on Quality Standards for Yinlian Oral Solution — Research Paper | ScholarLens