2008•Tianjin Journal of Traditional Chinese MedicineRequires access

Quality standard of QingYi tablet

Fan Jun-ting

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Abstract

[Objective] To establish the quality standard of QingYi Tablets (Radix Et RhiZoma Rhei ,Radix Paeoniae Alba, Rhizoma Picrorhizae).[Methods] Radix Et RniZomu Rhei ,Rellix Pheouiae Alba and Rnizoma Picrorhizal were identified by TLC. The content of Baicalin was determined by HPLC. The separation was performed on C18 Column with methanol-Water-Phosphorus acid (47:53:0.2) as a mobile phase. The flow rate was 1.0mL/min, detection Wavelength at 280 nm.[Results] The developed TLC spots were quite clear. The content of Baicalin can be determined by HPLC. The linearity of Baicalin was good in the range of 0.27-1.08ug. (r=0.999 8) The average recovery of Baicalin was 99.46%, RSD=0.39%(n=6). [Conclusion] The method was simple, reliable, accurate and can be applied as the quantity control method of QingYi Tablet.

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What this paper is about

[Objective] To establish the quality standard of QingYi Tablets (Radix Et RhiZoma Rhei ,Radix Paeoniae Alba, Rhizoma Picrorhizae).[Methods] Radix Et RniZomu Rhei ,Rellix Pheouiae Alba and Rnizoma Picrorhizal were identified by TLC. The content of Baicalin was determined by HPLC. The separation was performed on C18 Column with methanol-Water-Phosphorus acid (47:53:0.2) as a mobile phase. The flow rate was 1.0mL/min, detection Wavelength at 280 nm.[Results] The developed TLC spots were quite clear. The content of Baicalin can be determined by HPLC. The linearity of Baicalin was good in the range of 0.27-1.08ug. (r=0.999 8) The average recovery of Baicalin was 99.46%, RSD=0.39%(n=6). [Conclusion] The method was simple, reliable, accurate and can be applied as the quantity control method of QingYi Tablet.

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Available abstract

[Objective] To establish the quality standard of QingYi Tablets (Radix Et RhiZoma Rhei ,Radix Paeoniae Alba, Rhizoma Picrorhizae).[Methods] Radix Et RniZomu Rhei ,Rellix Pheouiae Alba and Rnizoma Picrorhizal were identified by TLC. The content of Baicalin was determined by HPLC. The separation was performed on C18 Column with methanol-Water-Phosphorus acid (47:53:0.2) as a mobile phase. The flow rate was 1.0mL/min, detection Wavelength at 280 nm.[Results] The developed TLC spots were quite clear. The content of Baicalin can be determined by HPLC. The linearity of Baicalin was good in the range of 0.27-1.08ug. (r=0.999 8) The average recovery of Baicalin was 99.46%, RSD=0.39%(n=6). [Conclusion] The method was simple, reliable, accurate and can be applied as the quantity control method of QingYi Tablet.

Key concepts: Baicalin, Radix (gastropod), Chromatography, Quality standard, High-performance liquid chromatography, Chemistry, Biology, Botany

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