Clinical observation of BiPAP ventilator in treating 30 cases of chronic obstructive pulmonary diseases with respiratory failure

Objective To determine the of BiPAP ventilator in treating chronic obstructive pulmonary diseases (COPD) combined with respiratory failure. Methods A total of 62 COPD patients combined with mild to moderate respiratory failure Type Ⅱ (pH 7.25-7.35) were randomly divided into control group, received routine therapy, and BiPAP group, received noninvasive ventilation by BiPAP ventilator (2 times per day, 4 h per time) on the basis of routine therapy. The blood gas analysis, heart rate, respiratory rate, Borg scale, and pulmonary function before and after treatment as well as intubation rate and days of hospitalization were determined. Results After the 3 d treatment, arterial pH and PaCO2 improved in both groups, but changes were more profound in the BiPAP group (P0. 05). The intubation rate was lower in the BiPAP group than that in the control group (P0.05). In patients with pH 7.31-7.35, these percentages were similar (P0.05). In patients with pH 7.25-7.30, the intubation rate was lower in the BiPAP group than that in the control group (P0.01). The duration in hospital was shorter in the BiPAP group than that in the control group (P0.05). Conclusion The use of BiPAP ventilator could improve the parameters of arterial pH and PaCO2 in COPD patients combined with mild to moderate respiratory failure Type Ⅱ, and particularly reduce the need for intubation and the duration in hospital for the patients with moderate respiratory failure Type Ⅱ.