Analysis on risk factors for early diabetes nephropathy and carotid atherosclerosis

Objective To investigate the early diabetes nephropathy(EDN)and atherosclerosis(AS),and analysis the related factors.Methods 58EDN patients were enrolled as an observation group and 58 type 2 diabetes mellitus(T2DM)patients as the control group.These two groups were observed AS changes.The observation group was further divided into two groups with AS or not AS.We assessed glycosylated hemoglobin(HbA1c),fasting blood glucose(FBG),three acids glyceride(TG),total cholesterol(TC),high density lipoprotein cholesterol(HDLC),low density lipoprotein cholesterol(LDL-C)among all the patients after 12-hour fasting,along with blood pressure,height,weight and body mass index(BMI)measurement.Results Carotid thickness and carotid atherosclerosis rate in observation group were significantly higher than the control group;Also the significant difference in terms of BMI,HbA1c,FBG,TG LDL-C and SBP between EDN with AS and EDN without AS was confirmed.Conclusion EDN is prone to have AS comparing to T2DM.And it is suggested that BMI,BP,HbA1c,FBG,TG,and LDL-C would be the potential risk factors for AS found in EDN patients.