2011Journal of Inner Mongolia University for the NationalitiesRequires access

Clinical Efficacy of Mongolian Medicine Wuweiqingzhuo San Combined with Simvastatin in Treatment of Hyperlipidemia

Tong Yu-qing

Open publisher page 0 citations

Abstract

Objective:To investigate the curative effect of Mongolian medicine Wuweiqingzhuo san combined with simvastatin in treatment of hyperlipidemia.Methods:80 hyperlipidemia patients were divided into two groups by using a randomized,control and single blind method,the treatment group(n=40)treated with Mongolian medicine Wuweiqingzhuo san(3g,third daily)plus simvastatin(30mg,once daily,) the control group(n=40)treated with simvastatin(30mg,once daily,) the teatment course were 8 weeks for both groups,and then observed the change of blood lipid.Results:In the treatment group,the serum total cholesterol(TC,) triglyceride(TG),low density lipoprotein cholesterol(LDL-C)were significantly lower than before treatment(P0.01,) high density lipoprotein cholesterol(HDL-C)increased(P0.01.) In the control group,TC,TG,LDL-C also significantly reduced(P 0.01,) HDL-L increased(P0.05.) When comparing the reduced degree of TC,TG,LDL-C in the two groups,the treatment group obviously superior than the control group(P0.05 or P0.01.) Conclusion:Combined using the two drugs has a significant lipid-decreasing effect,which provide an evidence for treatment of hyperlipidemia with Mongolian medicine combined with Western medicine.

About this research paper

What this paper is about

Objective:To investigate the curative effect of Mongolian medicine Wuweiqingzhuo san combined with simvastatin in treatment of hyperlipidemia.Methods:80 hyperlipidemia patients were divided into two groups by using a randomized,control and single blind method,the treatment group(n=40)treated with Mongolian medicine Wuweiqingzhuo san(3g,third daily)plus simvastatin(30mg,once daily,) the control group(n=40)treated with simvastatin(30mg,once daily,) the teatment course were 8 weeks for both groups,and then observed the change of blood lipid.Results:In the treatment group,the serum total cholesterol(TC,) triglyceride(TG),low density lipoprotein cholesterol(LDL-C)were significantly lower than before treatment(P0.01,) high density lipoprotein cholesterol(HDL-C)increased(P0.01.) In the control group,TC,TG,LDL-C also significantly reduced(P 0.01,) HDL-L increased(P0.05.) When comparing the reduced degree of TC,TG,LDL-C in the two groups,the treatment group obviously superior than the control group(P0.05 or P0.01.) Conclusion:Combined using the two drugs has a significant lipid-decreasing effect,which provide an evidence for treatment of hyperlipidemia with Mongolian medicine combined with Western medicine.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective:To investigate the curative effect of Mongolian medicine Wuweiqingzhuo san combined with simvastatin in treatment of hyperlipidemia.Methods:80 hyperlipidemia patients were divided into two groups by using a randomized,control and single blind method,the treatment group(n=40)treated with Mongolian medicine Wuweiqingzhuo san(3g,third daily)plus simvastatin(30mg,once daily,) the control group(n=40)treated with simvastatin(30mg,once daily,) the teatment course were 8 weeks for both groups,and then observed the change of blood lipid.Results:In the treatment group,the serum total cholesterol(TC,) triglyceride(TG),low density lipoprotein cholesterol(LDL-C)were significantly lower than before treatment(P0.01,) high density lipoprotein cholesterol(HDL-C)increased(P0.01.) In the control group,TC,TG,LDL-C also significantly reduced(P 0.01,) HDL-L increased(P0.05.) When comparing the reduced degree of TC,TG,LDL-C in the two groups,the treatment group obviously superior than the control group(P0.05 or P0.01.) Conclusion:Combined using the two drugs has a significant lipid-decreasing effect,which provide an evidence for treatment of hyperlipidemia with Mongolian medicine combined with Western medicine.

Key concepts: Simvastatin, Hyperlipidemia, Triglyceride, Medicine, High-density lipoprotein, Blood lipids, Cholesterol, Internal medicine

Related papers

Back to paper searchBrowse research topicsOriginal source
Clinical Efficacy of Mongolian Medicine Wuweiqingzhuo San Combined with Simvastatin in Treatment of Hyperlipidemia — Research Paper | ScholarLens