Clinical Efficacy of Mongolian Medicine Wuweiqingzhuo San Combined with Simvastatin in Treatment of Hyperlipidemia
Tong Yu-qing
Abstract
Tong Yu-qing
Abstract
Objective:To investigate the curative effect of Mongolian medicine Wuweiqingzhuo san combined with simvastatin in treatment of hyperlipidemia.Methods:80 hyperlipidemia patients were divided into two groups by using a randomized,control and single blind method,the treatment group(n=40)treated with Mongolian medicine Wuweiqingzhuo san(3g,third daily)plus simvastatin(30mg,once daily,) the control group(n=40)treated with simvastatin(30mg,once daily,) the teatment course were 8 weeks for both groups,and then observed the change of blood lipid.Results:In the treatment group,the serum total cholesterol(TC,) triglyceride(TG),low density lipoprotein cholesterol(LDL-C)were significantly lower than before treatment(P0.01,) high density lipoprotein cholesterol(HDL-C)increased(P0.01.) In the control group,TC,TG,LDL-C also significantly reduced(P 0.01,) HDL-L increased(P0.05.) When comparing the reduced degree of TC,TG,LDL-C in the two groups,the treatment group obviously superior than the control group(P0.05 or P0.01.) Conclusion:Combined using the two drugs has a significant lipid-decreasing effect,which provide an evidence for treatment of hyperlipidemia with Mongolian medicine combined with Western medicine.
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Objective:To investigate the curative effect of Mongolian medicine Wuweiqingzhuo san combined with simvastatin in treatment of hyperlipidemia.Methods:80 hyperlipidemia patients were divided into two groups by using a randomized,control and single blind method,the treatment group(n=40)treated with Mongolian medicine Wuweiqingzhuo san(3g,third daily)plus simvastatin(30mg,once daily,) the control group(n=40)treated with simvastatin(30mg,once daily,) the teatment course were 8 weeks for both groups,and then observed the change of blood lipid.Results:In the treatment group,the serum total cholesterol(TC,) triglyceride(TG),low density lipoprotein cholesterol(LDL-C)were significantly lower than before treatment(P0.01,) high density lipoprotein cholesterol(HDL-C)increased(P0.01.) In the control group,TC,TG,LDL-C also significantly reduced(P 0.01,) HDL-L increased(P0.05.) When comparing the reduced degree of TC,TG,LDL-C in the two groups,the treatment group obviously superior than the control group(P0.05 or P0.01.) Conclusion:Combined using the two drugs has a significant lipid-decreasing effect,which provide an evidence for treatment of hyperlipidemia with Mongolian medicine combined with Western medicine.
Key concepts: Simvastatin, Hyperlipidemia, Triglyceride, Medicine, High-density lipoprotein, Blood lipids, Cholesterol, Internal medicine