Evaluation for the Efficacy of Taizhian in Treatment of Primary Hyperlipidemia in Aged Patients

Objective To study the efficacy and safety of Taizhian in treatment of aged patients with primary hyperlipidemia.Methods Sixty patients with hyperlipidemia were divided into two groups.Taizhian and simvastatin of 10mg/d group have 30 patients (group A),simultaneously were given simvastatin 10mg before sleep and Taizhian three pills,po,tid for 8wk;30 patients (group B) were given simvastatim 20mg,before sleep for 8 wk.By using full-anutomatic biochemical analytic instrument to measure all lipidemia markers.Results In these two groups,the levels of TC,TG,LDL-C,AI decreased and HDL-C increased(P0 05 or 0 01).The levels of TC,TG and LDL-C were decreased with 27 48%,19 92%,25 90% respectively in Taizhian group,with 24 95%,17 11%,27 99% in simvastatin group.HDL-C increased in the two groups,these were 35 37% and 53 44% respectively.There were significantly difference in these two groups before and after treatment (P0 05),but not between them(P0 05).In the two groups the adverse reaction were mild.Conclustions Taizhian and simvastatin of 10mg/d are so effective in treatment hyperlipidemia as simvastatin of 20mg/d,while the former can decrease the adverse reaction.